Clinical, histopathological and immunofluorescent findings of IgA nephropathy.

Comment on: Clinical, Histopathological and Immunofluorescent Findings of IgA Nephropathy

Clinical, Histopathological and Immunofluorescent Findings of IgA Nephropathy

Background: IgA nephropathy, a prevalent disease in Asia, is considered the main cause of end stage renal disease among primary glomerular disease. Objective: To determine the frequency of different clinical, histopathological and immunofluorescent characteristics of IgA nephropathy. Methods: Renal biopsies of 376 patients were received for immunofluorescent and for histopathological studies. B...

Comment on: clinical, histopathological and immunofluorescent findings of IgA nephropathy.

We read with interest the recently published article by Tipu et al. entitled “Clinical, histopathological and immunofluorescent findings of IgA nephropathy”, in the esteemed Iranian Journal of Immunology (1). The study described frequency of different clinical, histopathological and immunofluorescent characteristics of IgA nephropathy. The authors should be applauded for their findings; however...

IgA nephropathy.

A great interest in IgA nephropathy was demonstrated in the last few years. Unfortunately, a complete picture of this chronic disease should not yet been made. The article deals with 7 patients with IgA nephropathy treated in our Institute. The following characteristics were examined during a long period of time (1-17 years): clinical picture, course of the disease, clinical and morphologic cor...

Do IgA antigliadin and IgA antiendomysium antibodies show there is latent coeliac disease in primary IgA nephropathy?

The finding in primary IgA nephropathy of increased levels of IgA to food antigens and particularly to gliadin prompted the hypothesis that a subgroup of these patients may have latent coeliac disease. The observation that gliadin may experimentally induce IgA mesangial deposits supported this hypothesis. We evaluated specific immunological markers of coeliac disease (antiendomysium antibodies)...